Study on lead2excretion effect of carambola juice in lead2exposed mice

TI:Study on lead2excretion effect of carambola juice in lead2exposed mice
AU:LIU Xiuying , HU Yixiu , ZANG Xuebing , FAN Di , LIU Fuqiang ,ZHOU Yuechan , HU Chunsheng , HU Yuming , NIE Yan
AD:(Hunan Provincial Center for Disease Control and Prevention , Hunan Changsha 410005 , China)
Abstract : To test the lead2excretion effect of a carambola juice , 4 groups of mice were exposed to lead in deionized drinking water at 546122 Pb2 + mgPL concentration , and 3 of them were additionally administered with carambola juice by gavage at doses of 1010、2010 and 4010 mlPkg BW respectively for 30 days. The mice in a fifth blank control group unexposed to lead were given deionized water. The amounts of water drunk by each group of mice during the experiment were recorded. At the end of the experiment , samples of whole blood , liver and femur were collected for lead detection by atomic absorption spectroscopy. Mice in different lead - exposed groups ingested comparable doses of lead. Treatment with the test substance resulted in signifi2 cant decrease in blood lead concentration and lead content in liver. The test substance produced no significant effect on lead concentration in femurs. It could be concluded that the carambola juice could promote lead excretion in mice.
Key word : ACTINIDIA CHINENSIS; Lead ; Mice ; Animals , Laboratory

Chinese center for disease control andprevention
  Chinese Center for Disease Control and Prevention (China CDC)
155 Changbai Road Changping District| Beijing | 102206 | People's Republic of China
Copyright @ China CDC 2010